# Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients(neoR-TORCH)

Source: https://onco.cc/trials/nct06437977/  
OnCo record `nct06437977` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of toripalimab in lung cancer, run by Shanghai Chest Hospital, now recruiting.

## Summary

Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients(neoR-TORCH) is a phase 3, randomised interventional study registered as NCT06437977 by Shanghai Chest Hospital, with a registry enrolment figure of 478 participants, started 2024-09-12 and due to reach its primary completion in 2027-06. Interventions recorded: SBRT; Toripalimab. Conditions listed: Stage II-III Non-small Cell Lung Cancer. Primary outcome: 2-year Event Free Survival Rate; pCR rate. Lung eligibility wording from the registry: "Treatment-naive, histologically confirmed resectable, stage II, IIIA, IIIB (N2) (AJCC staging system, version 8) NSCLC ;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Also known as: neoR-TORCH
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06437977
- Phase: 3
- Setting: Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients: A Multicenter, Openlabel, Randomized, Phase III Trial
- Sponsor: Shanghai Chest Hospital
- Enrolled: 478

## Sources

- ClinicalTrials.gov NCT06437977: https://clinicaltrials.gov/study/NCT06437977

## Connected records

- cancers: [Resectable stage I to III non-small-cell lung cancer](https://onco.cc/cancers/resectable-nsclc/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/), [SBRT / SABR (stereotactic radiotherapy)](https://onco.cc/technologies/sbrt/)
- drugs: [Toripalimab](https://onco.cc/drugs/toripalimab/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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