# Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer

Source: https://onco.cc/trials/nct06523673/  
OnCo record `nct06523673` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in lung cancer, run by Second Affiliated Hospital, Zhejiang University, School of Medicine, now recruiting.

## Summary

Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT06523673 by Second Affiliated Hospital, Zhejiang University, School of Medicine, with a registry enrolment figure of 104 participants, started 2024-09 and due to reach its primary completion in 2027-09. Interventions recorded: Stereotactic Body Radiotherapy; second-line systemic therapy. Conditions listed: Metastatic Non-Small Cell Lung Cancer; NSCLC Stage IV; OligoProgressive Metastatic Disease. Primary outcome: progression-free survival (PFS). Lung eligibility wording from the registry: "* Histologically and/or cytologically confirmed stage IV metastatic NSCLC". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Also known as: OPPRESS
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06523673
- Phase: 3
- Setting: Stereotactic Body Radiotherapy (SBRT) for Oligo-Progression During First-Line Chemotherapy in Metastatic Non-Small Cell Lung Cancer (OPPRESS):A Randomized, Controlled, Open-label, Multi-Center Phase 3 Study
- Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine
- Enrolled: 104

## Sources

- ClinicalTrials.gov NCT06523673: https://clinicaltrials.gov/study/NCT06523673

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- technologies: [SBRT / SABR (stereotactic radiotherapy)](https://onco.cc/technologies/sbrt/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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