# Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

Source: https://onco.cc/trials/nct06535607/  
OnCo record `nct06535607` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Cisplatin, Carboplatin, Paclitaxel / nab-paclitaxel in cervical cancer and head and neck squamous cell carcinoma, run by AstraZeneca, now recruiting.

## Summary

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors is a phase 2 interventional study registered as NCT06535607 by AstraZeneca, with 257 participants planned, started 2024-08-22 and due to reach its primary completion in 2028-11-30. Interventions recorded: Volrustomig, Cisplatin, Carboplatin, Paclitaxel, 5-FU. Conditions listed: Sub-study 1 Cervical Cancer (Volrustomig Monotherapy), Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy), Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy), Sub-study 4 Esophageal Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy). No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT06535607
- Phase: 2
- Setting: A Phase II, Multi-Center Study to Evaluate the Efficacy and Safety of Volrustomig as Monotherapy or in Combination With Anti-cancer Agents in Participants With Advanced/Metastatic Solid Tumors
- Sponsor: AstraZeneca
- Enrolled: 257

## Sources

- ClinicalTrials.gov NCT06535607: https://clinicaltrials.gov/study/NCT06535607

## Connected records

- cancers: [Cervical cancer](https://onco.cc/cancers/cervical/), [Head and neck squamous cell carcinoma](https://onco.cc/cancers/head-and-neck/), [Mesothelioma](https://onco.cc/cancers/mesothelioma/)
- drugs: [Carboplatin](https://onco.cc/drugs/carboplatin/), [Cisplatin](https://onco.cc/drugs/cisplatin/), [FLOT (5-FU, leucovorin, oxaliplatin, docetaxel)](https://onco.cc/drugs/flot/), [Paclitaxel / nab-paclitaxel](https://onco.cc/drugs/paclitaxel/)
- companies: [AstraZeneca](https://onco.cc/companies/astrazeneca/)

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