# Emapalumab Prevention of CAR-T Cell Associated Toxicities

Source: https://onco.cc/trials/nct06550141/  
OnCo record `nct06550141` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Emapalumab, Cyclophosphamide, Fludarabine and Axicabtagene ciloleucel in Non-Hodgkin lymphoma, Diffuse large B-cell lymphoma, Primary mediastinal and Follicular lymphoma, run by Marcela V. Maus, M.D.,Ph.D., now recruiting.

## Summary

Emapalumab Prevention of CAR-T Cell Associated Toxicities is a phase 2 interventional study registered as NCT06550141 by Marcela V. Maus, M.D.,Ph.D., with 28 participants planned, started 2024-09-18 and due to reach its primary completion in 2026-08-01. Interventions recorded: Emapalumab, Cyclophosphamide, Fludarabine Phosphate, Axicabtagene Ciloleucel. Conditions recorded: Large B-cell Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma, High-grade B-cell Lymphoma, Follicular Lymphoma.

Linked to the drug Emapalumab because the registry names it among its interventions and Non-Hodgkin lymphoma, Diffuse large B-cell lymphoma, Primary mediastinal and Follicular lymphoma among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT06550141
- Phase: 2
- Setting: A Phase 2 Trial of Emapalumab for the Prevention of CAR-T Cell Associated Toxicities
- Sponsor: Marcela V. Maus, M.D.,Ph.D.
- Enrolled: 28

## Sources

- ClinicalTrials.gov NCT06550141: https://clinicaltrials.gov/study/NCT06550141

## Connected records

- cancers: [Diffuse large B-cell lymphoma](https://onco.cc/cancers/dlbcl/), [Follicular lymphoma](https://onco.cc/cancers/follicular-lymphoma/), [Non-Hodgkin lymphoma (all types)](https://onco.cc/cancers/non-hodgkin-lymphoma/), [Primary mediastinal (thymic) large B-cell lymphoma](https://onco.cc/cancers/primary-mediastinal-b-cell-lymphoma/)
- drugs: [Axicabtagene ciloleucel](https://onco.cc/drugs/axicabtagene-ciloleucel/), [Cyclophosphamide](https://onco.cc/drugs/cyclophosphamide/), [Emapalumab](https://onco.cc/drugs/emapalumab/), [Fludarabine](https://onco.cc/drugs/fludarabine/)

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JSON: https://onco.cc/api/v1/entities/nct06550141.json