# JK-1201I Compared with Topotecan in Patients with Relapsed Extensive Stage Small Cell Lung Cancer

Source: https://onco.cc/trials/nct06581380/  
OnCo record `nct06581380` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of topotecan in lung cancer, run by JenKem Technology Co., Ltd., not yet recruiting.

## Summary

JK-1201I Compared with Topotecan in Patients with Relapsed Extensive Stage Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT06581380 by JenKem Technology Co., Ltd., with a registry enrolment figure of 394 participants, started 2024-09-16 and due to reach its primary completion in 2027-11-16. Interventions recorded: JK-1201I; Topotecan. Conditions listed: Small Cell Lung Cancer. Primary outcome: Overall survival (OS). Lung eligibility wording from the registry: "Histologically or cytologically documented SCLC". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06581380
- Phase: 3
- Setting: A Multicenter, Randomized, Positive-Controlled, Open-label, Phase 3 Study of JK-1201I Compared with Topotecan in Patients with Relapsed Extensive Stage Small Cell Lung Cancer After Platinum-based First-line Chemotherapy
- Sponsor: JenKem Technology Co., Ltd.
- Enrolled: 394

## Sources

- ClinicalTrials.gov NCT06581380: https://clinicaltrials.gov/study/NCT06581380

## Connected records

- cancers: [Extensive-stage small-cell lung cancer](https://onco.cc/cancers/extensive-stage-sclc/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Topoisomerase-I inhibitors (and ADC payloads)](https://onco.cc/technologies/topoisomerase-inhibitors/)
- drugs: [Topotecan](https://onco.cc/drugs/topotecan/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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