# ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study

Source: https://onco.cc/trials/nct06609551/  
OnCo record `nct06609551` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in colorectal cancer, run by Zhejiang Cancer Hospital, now recruiting.

## Summary

ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study is a phase 3, randomised interventional study registered as NCT06609551 by Zhejiang Cancer Hospital, with a registry enrolment figure of 312 participants, started 2024-07-03 and due to reach its primary completion in 2029-12-31. Interventions recorded: 6-month adjuvant chemotherapy with 5-FU monotherapy; XELOX intensive treatment group. Conditions listed: Colon Cancer; Colon Cancer (Stage II &Amp;Amp;Amp; III). Primary outcome: 2-year DFS (Disease-Free Survival). Colorectal eligibility wording from the registry: "Patients with histopathologically confirmed stage II high-risk or stage III colon cancer;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: ZJCH-CRCC-1
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06609551
- Phase: 3
- Setting: ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study
- Sponsor: Zhejiang Cancer Hospital
- Enrolled: 312

## Sources

- ClinicalTrials.gov NCT06609551: https://clinicaltrials.gov/study/NCT06609551

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- technologies: [MRD / molecular residual disease testing](https://onco.cc/technologies/mrd-testing/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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