# First-line Treatment of MCapOX + Cetuximab Vs. MFOLFOX6 + Cetuximab for RAS/BRAF Wild-type, MSS, Unresectable Left-Sided MCRC: a Multicenter, Randomized, Contro

Source: https://onco.cc/trials/nct06616259/  
OnCo record `nct06616259` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in colorectal cancer, run by Meng Qiu, not yet recruiting.

## Summary

First-line Treatment of MCapOX + Cetuximab Vs. MFOLFOX6 + Cetuximab for RAS/BRAF Wild-type, MSS, Unresectable Left-Sided MCRC: a Multicenter, Randomized, Controlled, Phase III Study is a phase 3, randomised interventional study registered as NCT06616259 by Meng Qiu, with a registry enrolment figure of 452 participants, started 2024-09-26 and due to reach its primary completion in 2028-09-30. Interventions recorded: mCapOX plus Cetuximab; mFOLFOX6 plus Cetuximab. Conditions listed: Colorectal Cancer (CRC); Capecitabine; Cetuximab. Primary outcome: Progression free survival (PFS). Colorectal eligibility wording from the registry: "* Patients with histologically or cytologically confirmed RAS and BRAF wild-type, MSS/pMMR, metastatic left-sided colorectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: CAPCET-III
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06616259
- Phase: 3
- Setting: First-line Treatment of MCapOX in Combination with Cetuximab Versus MFOLFOX6 in Combination with Cetuximab for RAS/BRAF Wild-type, MSS, Unresectable Left-Sided Metastatic Colorectal Cancer: a Multicenter, Randomized, Controlled, Phase III Study
- Sponsor: Meng Qiu
- Enrolled: 452

## Sources

- ClinicalTrials.gov NCT06616259: https://clinicaltrials.gov/study/NCT06616259

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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