# Anlotinib Plus Benmelstobart and AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer (ALTER-PA-001)

Source: https://onco.cc/trials/nct06621095/  
OnCo record `nct06621095` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of gemcitabine + nab-paclitaxel in pancreatic cancer, run by RenJi Hospital, not yet recruiting.

## Summary

Anlotinib Plus Benmelstobart and AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer (ALTER-PA-001) is a phase 2, randomised interventional study registered as NCT06621095 by RenJi Hospital, with a registry enrolment figure of 104 participants, started 2024-10-30 and due to reach its primary completion in 2025-12-31. Interventions recorded: anlotinib + benmelstobart + nab-paclitaxel + gemcitabine; nab-paclitaxel + gemcitabine. Conditions listed: Pancreatic Cancer; First-line; Metastatic Pancreatic Cancer. Primary outcome: Objective response rate (ORR). Pancreatic eligibility wording from the registry: "* Histologically or cytologically confirmed diagnosis of metastatic pancreatic cancer;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06621095
- Phase: 2
- Setting: Anlotinib Plus Benmelstobart and AG Versus AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer: a Prospective, Randomized Controlled Clinical Trial (ALTER-PA-001)
- Sponsor: RenJi Hospital
- Enrolled: 104

## Sources

- ClinicalTrials.gov NCT06621095: https://clinicaltrials.gov/study/NCT06621095

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Gemcitabine + nab-paclitaxel](https://onco.cc/drugs/gemcitabine-nab-paclitaxel/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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