# Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01）

Source: https://onco.cc/trials/nct06647680/  
OnCo record `nct06647680` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of capecitabine in colorectal cancer, run by The Affiliated Hospital of Qingdao University, now recruiting.

## Summary

Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01） is a phase 2, interventional study registered as NCT06647680 by The Affiliated Hospital of Qingdao University, with a registry enrolment figure of 35 participants, started 2025-06-01 and due to reach its primary completion in 2026-12-01. Interventions recorded: Receive the experimental combination of drugs (chemoradiation (Oxaliplatin and Capecitabine) + PD-1 inhibitor (Tislelizumab) for 3 cycles. Conditions listed: Rectal Cancer Patients. Primary outcome: Clinical complete response and pathological complete response. Colorectal eligibility wording from the registry: "* Pathologically proven diagnosis of adenocarcinoma of the rectum". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06647680
- Phase: 2
- Setting: Neoadjuvant Chemotherapy and Tislelizumab (PD-1 Inhibitior) for Locally Advanced Rectal Cancer: a Single-center, Prospective, Phase II Study
- Sponsor: The Affiliated Hospital of Qingdao University
- Enrolled: 35

## Sources

- ClinicalTrials.gov NCT06647680: https://clinicaltrials.gov/study/NCT06647680

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- drugs: [Capecitabine](https://onco.cc/drugs/capecitabine/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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