# CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC

Source: https://onco.cc/trials/nct06665087/  
OnCo record `nct06665087` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Fudan University, not yet recruiting.

## Summary

CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRC is a phase 2, interventional study registered as NCT06665087 by Fudan University, with a registry enrolment figure of 110 participants, started 2024-11 and due to reach its primary completion in 2027-11. Interventions recorded: Ultrafractionated RT and CGA Guided systemic treatment.; Ultrafractionated Radiotherapy; PD-1 antibody; Chemotherapy (Fluorouracil); Chemotherapy (Raltitrexed); Chemotherapy (Oxaliplatin); Chemotherapy (CPT-11); Targeted Therapy (anti-VEGF); Targeted Therapy (anti-EGFR). Conditions listed: Colon Cancer; Rectal Cancer. Primary outcome: Progression Free Survival. Colorectal eligibility wording from the registry: "metastatic colorectal cancer;". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06665087
- Phase: 2
- Setting: Comprehensive Geriatric Assessment (CGA) Guided Ultrafractionated Radiotherapy and First-line Systemic Treatment in Elderly or Frail Patients with Metastatic Colorectal Cancer
- Sponsor: Fudan University
- Enrolled: 110

## Sources

- ClinicalTrials.gov NCT06665087: https://clinicaltrials.gov/study/NCT06665087

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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