# SHR-A1811 Combined with Apatinib in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer

Source: https://onco.cc/trials/nct06666166/  
OnCo record `nct06666166` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Yunpeng Liu, not yet recruiting.

## Summary

SHR-A1811 Combined with Apatinib in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer is a phase 2, interventional study registered as NCT06666166 by Yunpeng Liu, with a registry enrolment figure of 28 participants, started 2024-12 and due to reach its primary completion in 2028-07. Interventions recorded: SHR-A1811 & Apartinib. Conditions listed: Advanced Gastric Carcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Advanced Colorectal Cancer. Primary outcome: Objective response rate (ORR). Colorectal eligibility wording from the registry: "The function of major organs meets the following criteria(not transfused, not using haematopoietic factors and not corrected with drugs within 14 days):". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06666166
- Phase: 2
- Setting: Exploratory Clinical Study of SHR-A1811 Combined with Apatinib in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma and Colorectal Cancer
- Sponsor: Yunpeng Liu
- Enrolled: 28

## Sources

- ClinicalTrials.gov NCT06666166: https://clinicaltrials.gov/study/NCT06666166

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- companies: [Jiangsu Hengrui Pharmaceuticals](https://onco.cc/companies/hengrui/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct06666166.json