# Systemic Antitumor Treatment with or Without Pressurized Intraperitoneal Aerosol Chemotherapy for Colon Peritoneal Metastases (PIPOX02)

Source: https://onco.cc/trials/nct06681038/  
OnCo record `nct06681038` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Institut Cancerologie de l'Ouest, not yet recruiting.

## Summary

Systemic Antitumor Treatment with or Without Pressurized Intraperitoneal Aerosol Chemotherapy for Colon Peritoneal Metastases (PIPOX02) is a phase 2, randomised interventional study registered as NCT06681038 by Institut Cancerologie de l'Ouest, with a registry enrolment figure of 114 participants, started 2025-02 and due to reach its primary completion in 2029-08. Interventions recorded: Standard Medical Therapy; PIPAC. Conditions listed: Peritoneal Metastases from Colorectal Cancer. Primary outcome: Progression free survival (PFS) between the two groups. Colorectal eligibility wording from the registry: "* Histopathologically confirmed colonic adenocarcinoma with synchronous or metachronous peritoneal metastasis (PM);". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: PIPOX02
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06681038
- Phase: 2
- Setting: Systemic Antitumor Treatment with or Without Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) for Colon Peritoneal Metastases - a Multicentre Phase II Randomized Trial (PIPOX02)
- Sponsor: Institut Cancerologie de l'Ouest
- Enrolled: 114

## Sources

- ClinicalTrials.gov NCT06681038: https://clinicaltrials.gov/study/NCT06681038

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- technologies: [HIPEC / PIPAC (intraperitoneal chemotherapy)](https://onco.cc/technologies/hipec/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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