# Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC

Source: https://onco.cc/trials/nct06714604/  
OnCo record `nct06714604` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in pancreatic cancer, run by Sahlgrenska University Hospital, now recruiting.

## Summary

Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC is a phase 3, randomised interventional study registered as NCT06714604 by Sahlgrenska University Hospital, with a registry enrolment figure of 432 participants, started 2023-10-18 and due to reach its primary completion in 2032-12-31. Interventions recorded: FOLFIRINOX or gemcitabine-nab-paclitaxel; FOLFIRINOX or gemcitabine-nab-paclitaxel. Conditions listed: Locally Advanced Pancreatic Adenocarcinoma; Borderline Resectable Pancreatic Carcinoma; Pancreas Cancer; Neoadjuvant Chemotherapy; Surgery; Pancreatectomy. Primary outcome: Overall survival of all BR/LAPC patients; Overall survival of all resected BR/LAPC patients. Pancreatic eligibility wording from the registry: "* Borderline or locally advanced pancreatic adenocarcinoma at diagnosis according to National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines, version 1". Sites: Sweden. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: ADVANTAGE
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06714604
- Phase: 3
- Setting: Standard Versus Prolonged Neoadjuvant (Conversion) Chemotherapy to Prolong Survival of Patients With Borderline and Locally Advanced Pancreatic Cancer: a Phase III Randomized Controlled
- Sponsor: Sahlgrenska University Hospital
- Enrolled: 432

## Sources

- ClinicalTrials.gov NCT06714604: https://clinicaltrials.gov/study/NCT06714604

## Connected records

- cancers: [Borderline resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/borderline-resectable-pdac/), [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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