# QL1706 Plus Chemotherapy With AG Regime as First-line Treatment of Advanced PDAC

Source: https://onco.cc/trials/nct06750861/  
OnCo record `nct06750861` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of iparomlimab and tuvonralimab in pancreatic cancer, run by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, not yet recruiting.

## Summary

QL1706 Plus Chemotherapy With AG Regime as First-line Treatment of Advanced PDAC is a phase 2, interventional study registered as NCT06750861 by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, with a registry enrolment figure of 30 participants, started 2025-02-15 and due to reach its primary completion in 2026-06-30. Interventions recorded: QL1706. Conditions listed: Pancreatic Adenocarcinoma. Primary outcome: Objective Response Rate (ORR); Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]. Pancreatic eligibility wording from the registry: "Has histologically or cytologically confirmed pancreatic ductal adenocarcinoma (PDAC);". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06750861
- Phase: 2
- Setting: QL1706 in Combination With Nab-paclitaxel and Gemcitabine as First-line Treatment in Patients With Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma : A Single-arm, Phase II Study
- Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT06750861: https://clinicaltrials.gov/study/NCT06750861

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- drugs: [Iparomlimab and tuvonralimab](https://onco.cc/drugs/iparomlimab-tuvonralimab/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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