# DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer

Source: https://onco.cc/trials/nct06757244/  
OnCo record `nct06757244` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of dostarlimab in pancreatic cancer, run by Hopital Foch, now recruiting.

## Summary

DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer is a phase 2, interventional study registered as NCT06757244 by Hopital Foch, with a registry enrolment figure of 35 participants, started 2025-02-18 and due to reach its primary completion in 2028-02-18. Interventions recorded: Dostarlimab; Vitamin D3 (Cholecalciferol); mFOLFIRINOX Treatment Regimen; LV5FU2. Conditions listed: Pancreas Neoplasms. Primary outcome: Objective response rate (ORR) according to Response Evaluation Criteria version 1.1 (RECIST 1.1) in patients with pancreatic adenocarcinoma and measurable disease. Pancreatic eligibility wording from the registry: "Histologically confirmed metastatic Stage IV adenocarcinoma of the pancreas". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: DOVIPA
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06757244
- Phase: 2
- Setting: DOVIPA, a Phase II Study Evaluating Efficacy and Safety of DOstarlimab and Oral VItamin D3 With Folinic Acid, 5FU, Irinotecan Plus Oxalipaltin (mFOLFIRINOX) in Non Pretreated Metastatic PAncreatic Cancer
- Sponsor: Hopital Foch
- Enrolled: 35

## Sources

- ClinicalTrials.gov NCT06757244: https://clinicaltrials.gov/study/NCT06757244

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Dostarlimab](https://onco.cc/drugs/dostarlimab/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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