# Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced Colorectal Cancer

Source: https://onco.cc/trials/nct06763029/  
OnCo record `nct06763029` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of cetuximab in colorectal cancer, run by Fudan University, now recruiting.

## Summary

Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced Colorectal Cancer is a phase 2, interventional study registered as NCT06763029 by Fudan University, with a registry enrolment figure of 36 participants, started 2025-02-26 and due to reach its primary completion in 2026-12-31. Interventions recorded: Irinotecan liposomes combined with cetuximab + vermofenib. Conditions listed: Colorectal Cancer Metastatic. Primary outcome: Objective response rate. Colorectal eligibility wording from the registry: "* Colorectal adenocarcinoma was confirmed by histological or cytopathological examination, and RAS wild /BRAF V600E mutation was detected by PCR or NGS;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: VICPROIRI
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06763029
- Phase: 2
- Setting: Phase II Exploratory Study of Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced RAS Wild /BRAF Mutated Colorectal Cancer
- Sponsor: Fudan University
- Enrolled: 36

## Sources

- ClinicalTrials.gov NCT06763029: https://clinicaltrials.gov/study/NCT06763029

## Connected records

- cancers: [BRAF V600E-mutant colorectal cancer](https://onco.cc/cancers/braf-v600e-colorectal/), [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Monoclonal antibodies](https://onco.cc/technologies/monoclonal-antibody/)
- drugs: [Cetuximab](https://onco.cc/drugs/cetuximab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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