# Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer

Source: https://onco.cc/trials/nct06765616/  
OnCo record `nct06765616` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Feng Tian, now recruiting.

## Summary

Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer is a phase 2, interventional study registered as NCT06765616 by Feng Tian, with a registry enrolment figure of 31 participants, started 2024-01-01 and due to reach its primary completion in 2025-07-01. Interventions recorded: Adebrelimab Injection combined with radiotherapy and chemotherapy. Conditions listed: Rectal Cancer; Advanced Stage Colorectal Cancer; Radiotherapy. Primary outcome: Pathological complete remission rate (pCR). Colorectal eligibility wording from the registry: "Patients diagnosed with rectal adenocarcinoma through primary lesion biopsy and histopathological examination;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06765616
- Phase: 2
- Setting: Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer: a Multicenter, Single Arm Prospective Study
- Sponsor: Feng Tian
- Enrolled: 31

## Sources

- ClinicalTrials.gov NCT06765616: https://clinicaltrials.gov/study/NCT06765616

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct06765616.json