# A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy

Source: https://onco.cc/trials/nct06769113/  
OnCo record `nct06769113` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of HLX43 in oesophageal cancer, run by Shanghai Henlius Biotech, now recruiting.

## Summary

A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy is a phase 2 interventional study registered as NCT06769113 by Shanghai Henlius Biotech, with 102 participants planned, started 2025-01-26 and due to reach its primary completion in 2026-10-31. Interventions recorded: HLX43.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-16
- Tags: pipeline; ctgov-ingest
- Registry id: NCT06769113
- Phase: 2
- Setting: A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Patients With Recurrent/Metastatic Esophageal Squamous Cell Carcinoma (ESCC) Failed or Intolerance to Standard First-line Therapy
- Sponsor: Shanghai Henlius Biotech
- Enrolled: 102

## Sources

- ClinicalTrials.gov NCT06769113: https://clinicaltrials.gov/study/NCT06769113

## Connected records

- cancers: [Oesophageal cancer](https://onco.cc/cancers/esophageal/)
- drugs: [HLX43](https://onco.cc/drugs/hlx43/)
- companies: [Shanghai Henlius Biotech](https://onco.cc/companies/henlius/)

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