# IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer

Source: https://onco.cc/trials/nct06770439/  
OnCo record `nct06770439` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of IBI343, gemcitabine and nab-paclitaxel in pancreatic cancer, run by Zhejiang University, now recruiting.

## Summary

IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer is a phase 2, randomised interventional study registered as NCT06770439 by Zhejiang University, with a registry enrolment figure of 64 participants, started 2025-04-18 and due to reach its primary completion in 2027-01. Interventions recorded: IBI343; Gemcitabine+Albumin-bound paclitaxel. Conditions listed: Advanced Pancreatic Cancers. Primary outcome: Objective Response Rate; Adverse Event. Pancreatic eligibility wording from the registry: "* Histopathologically confirmed unresectable locally advanced, recurrent, or metastatic pancreatic adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06770439
- Phase: 2
- Setting: A Phase II Study to Evaluate the Safety, Tolerability, and Efficacy of IBI343 Combined With Chemotherapy in Advanced Pancreatic Cancer
- Sponsor: Zhejiang University
- Enrolled: 64

## Sources

- ClinicalTrials.gov NCT06770439: https://clinicaltrials.gov/study/NCT06770439

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Antibody-drug conjugate (ADC)](https://onco.cc/technologies/adc/), [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Gemcitabine](https://onco.cc/drugs/gemcitabine/), [IBI343](https://onco.cc/drugs/ibi343/), [Nab-paclitaxel](https://onco.cc/drugs/nab-paclitaxel/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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