# Evaluation of JSKN016 in the Treatment of Advanced Non-small Cell Lung Cance： a Phase II Clinical Study

Source: https://onco.cc/trials/nct06775483/  
OnCo record `nct06775483` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of JSKN016 and docetaxel in lung cancer, run by Jiangsu Alphamab Biopharmaceuticals Co., Ltd, not yet recruiting.

## Summary

Evaluation of JSKN016 in the Treatment of Advanced Non-small Cell Lung Cance： a Phase II Clinical Study is a phase 2, randomised interventional study registered as NCT06775483 by Jiangsu Alphamab Biopharmaceuticals Co., Ltd, with a registry enrolment figure of 220 participants, started 2025-01-17 and due to reach its primary completion in 2027-06-30. Interventions recorded: JSKN016; Docetaxel. Conditions listed: Advanced Non-small Cell Lung Cancer. Primary outcome: ORR assessed by the investigator per RECIST v1.1; Safety reflected by AE. Lung eligibility wording from the registry: "Histologically or cytologically confirmed locally advanced or metastatic non-small cell lung cancer (NSCLC) that is not suitable for radical surgery and/or radical radiotherapy, and meets one of the following conditions: EGFR sensitive mutations, and failed treatment with EGFR-TKI; Driver gene negat". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06775483
- Phase: 2
- Setting: Evaluation of JSKN016 in the Treatment of Advanced Non-small Cell Lung Cance： a Phase II Clinical Study
- Sponsor: Jiangsu Alphamab Biopharmaceuticals Co., Ltd
- Enrolled: 220

## Sources

- ClinicalTrials.gov NCT06775483: https://clinicaltrials.gov/study/NCT06775483

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Docetaxel](https://onco.cc/drugs/docetaxel/), [JSKN016](https://onco.cc/drugs/jskn016/)
- companies: [Alphamab Oncology](https://onco.cc/companies/alphamab/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct06775483.json