# Clinical Study of Nanocrystalline Megestrol in Malnourished Patients With First-Line Non-Small Cell Lung Cancer

Source: https://onco.cc/trials/nct06828757/  
OnCo record `nct06828757` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in lung cancer, run by Hunan Province Tumor Hospital, not yet recruiting.

## Summary

Clinical Study of Nanocrystalline Megestrol in Malnourished Patients With First-Line Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT06828757 by Hunan Province Tumor Hospital, with a registry enrolment figure of 94 participants, started 2025-05-01 and due to reach its primary completion in 2026-12-31. Interventions recorded: nanocrystalline megestrol oral suspension + PD-1/L1 inhibitor combined with chemotherapy; PD-1/L1 inhibitor combined with chemotherapy. Conditions listed: Non Small Cell Lung Cancer. Primary outcome: Appetite improvement level; Weight improvement level. Lung eligibility wording from the registry: "(5) According to the 8th edition of the TNM stage classification of lung cancer with histological or cytologic evidence that cannot undergo complete surgical resection and cannot undergo radical synchronous/sequential chemoradiation and treatment ( IIIB/IIIC phase), metastatic (IV phase) NSCLC". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06828757
- Phase: 3
- Setting: A Phase III Prospective, Randomized, Parallel-Controlled Clinical Study of Nanocrystalline Megestrol in Malnourished Patients With First-Line Non-Small Cell Lung Cancer
- Sponsor: Hunan Province Tumor Hospital
- Enrolled: 94

## Sources

- ClinicalTrials.gov NCT06828757: https://clinicaltrials.gov/study/NCT06828757

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct06828757.json