# LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer

Source: https://onco.cc/trials/nct06831955/  
OnCo record `nct06831955` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in triple-negative breast cancer, run by Universitaire Ziekenhuizen KU Leuven, now recruiting.

## Summary

LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Therapy in Patients With Triple Negative Breast Cancer is a phase 2, randomised interventional study registered as NCT06831955 by Universitaire Ziekenhuizen KU Leuven, with a registry enrolment figure of 356 participants, started 2026-02-01 and due to reach its primary completion in 2028-09-01. Interventions recorded: Exercise Therapy; Fasting-Mimicking Diet; SOC. Conditions listed: Triple Negative Breast Cancer (TNBC), Early Setting. Triple-negative eligibility wording from the registry: "* The patient has a biopsy-confirmed diagnosis of stage II-III TNBC". Sites: Belgium. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: LESLIE
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT06831955
- Phase: 2
- Setting: The LESLIE Trial: LifEStyle Intervention to Enhance Efficacy of Neoadjuvant Systemic Therapy in Patients With Triple Negative Breast Cancer
- Sponsor: Universitaire Ziekenhuizen KU Leuven
- Enrolled: 356

## Sources

- ClinicalTrials.gov NCT06831955: https://clinicaltrials.gov/study/NCT06831955

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct06831955.json