# The Clinical Study of the Efficacy and Safety of Trop2-ADC Monotherapy or Combination Immunotherapy Strategy in the Treatment of Advanced Triple-negative Breast

Source: https://onco.cc/trials/nct06851299/  
OnCo record `nct06851299` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in triple-negative breast cancer, run by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, now recruiting.

## Summary

The Clinical Study of the Efficacy and Safety of Trop2-ADC Monotherapy or Combination Immunotherapy Strategy in the Treatment of Advanced Triple-negative Breast Cancer. is a phase 2, randomised interventional study registered as NCT06851299 by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, with a registry enrolment figure of 60 participants, started 2025-03-01 and due to reach its primary completion in 2027-04-30. Interventions recorded: trop2-ADC; ADC +anti-angiogenic drug; ADC + PD1 monoclonal antibody +anti-angiogenic drug. Conditions listed: Metastatic Triple-negative Breast Cancer. Triple-negative eligibility wording from the registry: "* 1\) adult female patients (aged 18-70 years) with metastatic triple negative breast cancer confirmed by pathology or imaging;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT06851299
- Phase: 2
- Setting: Randomized Controlled Clinical Study of Efficacy and Safety of Trop2-ADC Monotherapy or Combination Immunotherapy Strategies in the Treatment of Advanced Triple-negative Breast Cancer
- Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Enrolled: 60

## Sources

- ClinicalTrials.gov NCT06851299: https://clinicaltrials.gov/study/NCT06851299

## Connected records

- cancers: [Metastatic triple-negative breast cancer](https://onco.cc/cancers/tnbc-metastatic/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

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