# A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer

Source: https://onco.cc/trials/nct06866977/  
OnCo record `nct06866977` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial in pancreatic cancer, run by Xiangya Hospital of Central South University, not yet recruiting.

## Summary

A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer is a phase 1/2, interventional study registered as NCT06866977 by Xiangya Hospital of Central South University, with a registry enrolment figure of 10 participants, started 2025-03-12 and due to reach its primary completion in 2025-10-31. Interventions recorded: Oncolytic virus VRT106; Chemotherapy. Conditions listed: Pancreatic Cancer. Primary outcome: Safety and tolerability. Pancreatic eligibility wording from the registry: "* Have unresectable pancreatic cancer as determined by imaging or surgical exploration and locally advanced or metastatic pancreatic ductal adenocarcinoma (including adenosquamous carcinoma) as confirmed by histology or cytology". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06866977
- Phase: 1/2
- Setting: A Single-arm, Open-label Clinical Study to Evaluate the Efficacy and Safety of VRT106 in Combination With Chemotherapy for Advanced Pancreatic Cancer
- Sponsor: Xiangya Hospital of Central South University
- Enrolled: 10

## Sources

- ClinicalTrials.gov NCT06866977: https://clinicaltrials.gov/study/NCT06866977

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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