# Study to Evaluate the Use of Capecitabine in Monotherapy and in Combination With Oxaliplatin in Elderly Patients as Adjuvant Chemotherapy for Locally Advanced C

Source: https://onco.cc/trials/nct06888843/  
OnCo record `nct06888843` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of capecitabine and fOLFOX (5-FU, leucovorin, oxaliplatin) in colorectal cancer, run by Nizhny Novgorod Regional Clinical Oncology Center, now recruiting.

## Summary

Study to Evaluate the Use of Capecitabine in Monotherapy and in Combination With Oxaliplatin in Elderly Patients as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer. is a phase 2, randomised interventional study registered as NCT06888843 by Nizhny Novgorod Regional Clinical Oncology Center, with a registry enrolment figure of 160 participants, started 2025-02-01 and due to reach its primary completion in 2028-02-01. Interventions recorded: Capecitabine; Oxaliplatin. Conditions listed: Colorectal Cancer. Primary outcome: The disease free survival. Colorectal eligibility wording from the registry: "Morphologically confirmed diagnosis of colorectal cancer;". Sites: Russia. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: AHTCRR-1
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06888843
- Phase: 2
- Setting: A Single-center, Open-label, Randomized Phase II Study to Evaluate the Use of Capecitabine in Monotherapy and in Combination With Oxaliplatin in Elderly Patients as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer.
- Sponsor: Nizhny Novgorod Regional Clinical Oncology Center
- Enrolled: 160

## Sources

- ClinicalTrials.gov NCT06888843: https://clinicaltrials.gov/study/NCT06888843

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [Capecitabine](https://onco.cc/drugs/capecitabine/), [FOLFOX (5-FU, leucovorin, oxaliplatin)](https://onco.cc/drugs/folfox/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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