# Glumetinib Combined With Osimertinib Treatment for Non-Small Cell Lung Cancer Patients

Source: https://onco.cc/trials/nct06908772/  
OnCo record `nct06908772` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2/3 trial in lung cancer, run by Shanghai JMT-Bio Inc., not yet recruiting.

## Summary

Glumetinib Combined With Osimertinib Treatment for Non-Small Cell Lung Cancer Patients is a phase 2/3, randomised interventional study registered as NCT06908772 by Shanghai JMT-Bio Inc., with a registry enrolment figure of 390 participants, started 2025-04-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: Glumetinib Tablets; Osimertinib Mesylate Tablets; Glumetinib Tablets Placebo. Conditions listed: Recurrent or Metastatic NSCLC Patients With Classical EGFR Mutations Accompanied by MET Amplification or Overexpression. Primary outcome: Phase 2：ORR as assessed by IRC. Lung eligibility wording from the registry: "Patients with NSCLC who have unresectable locally advanced or metastatic disease; 4". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06908772
- Phase: 2/3
- Setting: A Multicenter Phase II/III Clinical Study on the Efficacy and Safety of Glumetinib Combined With Osimertinib as First-Line Treatment in Non-Small Cell Lung Cancer Patients With Classical EGFR Mutations Accompanied by MET Amplification or Overexpression
- Sponsor: Shanghai JMT-Bio Inc.
- Enrolled: 390

## Sources

- ClinicalTrials.gov NCT06908772: https://clinicaltrials.gov/study/NCT06908772

## Connected records

- cancers: [EGFR-mutated non-small-cell lung cancer](https://onco.cc/cancers/egfr-mutant-nsclc/), [MET exon 14 and MET-amplified non-small-cell lung cancer](https://onco.cc/cancers/met-altered-nsclc/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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