# Effect of Perioperative Intravenous Infusion of Lidocaine on the Postoperative Course and the Immune Response in Patients Undergoing Surgery for Colon Cancer -

Source: https://onco.cc/trials/nct06923787/  
OnCo record `nct06923787` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Institute of Oncology Ljubljana, now recruiting.

## Summary

Effect of Perioperative Intravenous Infusion of Lidocaine on the Postoperative Course and the Immune Response in Patients Undergoing Surgery for Colon Cancer - the PILDI Study is a phase 2, randomised interventional study registered as NCT06923787 by Institute of Oncology Ljubljana, with a registry enrolment figure of 100 participants, started 2026-02-03 and due to reach its primary completion in 2027-07-01. Interventions recorded: Lidocaine; Placebo. Conditions listed: Colon Cancer. Primary outcome: Difference in opioid use in 24 hours after surgery between arms. Colorectal eligibility wording from the registry: "* colon cancer of any stage of the disease for which elective laparoscopic colon resection and colonic anastomosis will be performed,". Sites: Slovenia. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: PILDI
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06923787
- Phase: 2
- Setting: Effect of Perioperative Intravenous Infusion of Lidocaine on the Postoperative Course and the Immune Response in Patients Undergoing Surgery for Colon Cancer - the PILDI Study
- Sponsor: Institute of Oncology Ljubljana
- Enrolled: 100

## Sources

- ClinicalTrials.gov NCT06923787: https://clinicaltrials.gov/study/NCT06923787

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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