# A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

Source: https://onco.cc/trials/nct06985147/  
OnCo record `nct06985147` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of DISC-3405 in myeloproliferative neoplasms, run by Disc Medicine, Inc, active and no longer recruiting.

## Summary

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV) is a phase 2 interventional study registered as NCT06985147 by Disc Medicine, Inc, with 60 participants enrolled, started 2025-08-12 and due to reach its primary completion in 2027-02. Interventions recorded: DISC-3405.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: pipeline; ctgov-ingest
- Registry id: NCT06985147
- Phase: 2
- Setting: A Phase 2, Open-Label Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DISC-3405 in Participants With Polycythemia Vera (PV)
- Sponsor: Disc Medicine, Inc
- Enrolled: 60

## Sources

- ClinicalTrials.gov NCT06985147: https://clinicaltrials.gov/study/NCT06985147

## Connected records

- cancers: [Myeloproliferative neoplasms (PV, ET, myelofibrosis)](https://onco.cc/cancers/myeloproliferative-neoplasms/)

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