# Envafolimab With Chemotherapy and Simvastatin in Advanced Biliary Tract Cancer

Source: https://onco.cc/trials/nct07003815/  
OnCo record `nct07003815` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of envafolimab, gemcitabine and cisplatin in gallbladder cancer and other biliary tract cancers, run by Tongji Hospital, not yet recruiting.

## Summary

Envafolimab With Chemotherapy and Simvastatin in Advanced Biliary Tract Cancer is a phase 2 interventional study registered as NCT07003815 by Tongji Hospital, with a registry enrolment figure of 62 participants, started 2025-06 and due to reach its primary completion in 2026-12. Interventions recorded: Envafolimab + Gemcitabine + Cisplatin + Simvastatin. Conditions listed: Biliary Tract Cancer, Advanced Cancer. Gallbladder cancer is named in the registry entry: "* Diagnosis : Histologically confirmed unresectable, locally advanced, or metastatic biliary tract adenocarcinoma (including intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gallbladder cancer).". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; gallbladder-deep-dive
- Registry id: NCT07003815
- Phase: 2
- Setting: A Single-Arm, Exploratory Clinical Study of Envafolimab Combined With Gemcitabine, Cisplatin, and Simvastatin for the Treatment of Locally Advanced or Metastatic BTC Patients
- Sponsor: Tongji Hospital
- Enrolled: 62

## Sources

- ClinicalTrials.gov NCT07003815: https://clinicaltrials.gov/study/NCT07003815

## Connected records

- cancers: [Biliary tract cancer (all types)](https://onco.cc/cancers/biliary-tract-cancer/), [Biliary tract cancer (cholangiocarcinoma)](https://onco.cc/cancers/cholangiocarcinoma/), [Extrahepatic cholangiocarcinoma (perihilar and distal)](https://onco.cc/cancers/extrahepatic-cholangiocarcinoma/), [Gallbladder cancer](https://onco.cc/cancers/gallbladder/), [Intrahepatic cholangiocarcinoma](https://onco.cc/cancers/intrahepatic-cholangiocarcinoma/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [Cisplatin](https://onco.cc/drugs/cisplatin/), [Envafolimab](https://onco.cc/drugs/envafolimab/), [Gemcitabine](https://onco.cc/drugs/gemcitabine/)
- terms: [Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups)](https://onco.cc/terms/gallbladder-cancer-in-biliary-trials/)

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