# Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial

Source: https://onco.cc/trials/nct07015892/  
OnCo record `nct07015892` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in lung cancer, run by Instituto de Investigación Biomédica de Salamanca, now recruiting.

## Summary

Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial is a phase 3, randomised interventional study registered as NCT07015892 by Instituto de Investigación Biomédica de Salamanca, with a registry enrolment figure of 300 participants, started 2026-03-01 and due to reach its primary completion in 2028-09-01. Interventions recorded: Thoracic Radiotherapy 45 Gy BID; Thoracic Radiotherapy 60 Gy BID; Thoracic Radiotherapy SIB 45-54 Gy BID. Conditions listed: Small Cell Lung Carcinoma. Primary outcome: Progression-Free Survival (PFS). Lung eligibility wording from the registry: "* Histologically confirmed diagnosis of small cell lung cancer (SCLC)". Sites: Spain. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Also known as: ESCALADOR
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07015892
- Phase: 3
- Setting: Phase III Randomized Clinical Trial to Evaluate the Efficacy and Safety of Twice-Daily Hyperfractionated Dose-Escalated Thoracic Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer (ESCALADOR Study)
- Sponsor: Instituto de Investigación Biomédica de Salamanca
- Enrolled: 300

## Sources

- ClinicalTrials.gov NCT07015892: https://clinicaltrials.gov/study/NCT07015892

## Connected records

- cancers: [Limited-stage small-cell lung cancer](https://onco.cc/cancers/limited-stage-sclc/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07015892.json