# A Phase Ib/II Clinical Study of Regorafenib Combined With Toripalimab and Albumin-bound Paclitaxel for the Third-line Treatment of Advanced Pancreatic Cancer

Source: https://onco.cc/trials/nct07040228/  
OnCo record `nct07040228` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of regorafenib and toripalimab in pancreatic cancer, run by Junjie Hang, now recruiting.

## Summary

A Phase Ib/II Clinical Study of Regorafenib Combined With Toripalimab and Albumin-bound Paclitaxel for the Third-line Treatment of Advanced Pancreatic Cancer is a phase 1/2, interventional study registered as NCT07040228 by Junjie Hang, with a registry enrolment figure of 23 participants, started 2025-05-26 and due to reach its primary completion in 2027-05-30. Interventions recorded: Regorafenib combined with Toripalimab and Albumin paclitaxel. Conditions listed: Pancreatic Cancer Metastatic. Primary outcome: (PFS). Pancreatic eligibility wording from the registry: "Patients with unresectable/metastatic pancreatic cancer confirmed by histopathology;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07040228
- Phase: 1/2
- Setting: A Phase Ib/II Clinical Study of Regorafenib Combined With Toripalimab and Albumin-bound Paclitaxel for the Third-line Treatment of Advanced Pancreatic Cancer
- Sponsor: Junjie Hang
- Enrolled: 23

## Sources

- ClinicalTrials.gov NCT07040228: https://clinicaltrials.gov/study/NCT07040228

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Regorafenib](https://onco.cc/drugs/regorafenib/), [Toripalimab](https://onco.cc/drugs/toripalimab/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07040228.json