# Risk-adapted Adjuvant Chemotherapy Guided by the Tumour Stage for Operated Pancreatic Adenocarcinoma Following Neoadjuvant Chemotherapy With mFOLFIRINOX

Source: https://onco.cc/trials/nct07044453/  
OnCo record `nct07044453` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2/3 trial in pancreatic cancer, run by University Hospital, Rouen, now recruiting.

## Summary

Risk-adapted Adjuvant Chemotherapy Guided by the Tumour Stage for Operated Pancreatic Adenocarcinoma Following Neoadjuvant Chemotherapy With mFOLFIRINOX is a phase 2/3, randomised interventional study registered as NCT07044453 by University Hospital, Rouen, with a registry enrolment figure of 390 participants, started 2025-12-08 and due to reach its primary completion in 2030-09. Interventions recorded: Gem/Nabpaclitaxel infusion; mFOLFIRINOX infusion. Conditions listed: Resected Pancreatic Adenocarcinoma. Primary outcome: Disease Free Survival; Overall Survival. Pancreatic eligibility wording from the registry: "Histologically confirmed resected pancreatic adenocarcinoma (R0 or R1) that has received 3 months of neoadjuvant mFOLFIRINOX, including anatomically resectable and borderline resectable tumors, in accordance with the definitions and therapeutic considerations provided in the TNCD (2024) and ESMO (20". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: PANACHE 02
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07044453
- Phase: 2/3
- Setting: Risk-adapted Adjuvant Chemotherapy Guided by the Tumour Stage for Operated Pancreatic Adenocarcinoma Following Neoadjuvant Chemotherapy With mFOLFIRINOX - A Multicenter, FRENCH-PRODIGE Randomized Comparative Phase II/III Trial FRENCH26 - PRODIGE93 - PANACHE 02 Trial
- Sponsor: University Hospital, Rouen
- Enrolled: 390

## Sources

- ClinicalTrials.gov NCT07044453: https://clinicaltrials.gov/study/NCT07044453

## Connected records

- cancers: [Borderline resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/borderline-resectable-pdac/), [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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