# Liposomal Irinotecan (II) Fractionated Dosing Combined With 5-FU/LV (FOLFIRInali-3) and Bevacizumab in Second-line Treatment of Advanced Colorectal Cancer: A Si

Source: https://onco.cc/trials/nct07047560/  
OnCo record `nct07047560` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Tianjin Medical University Cancer Institute and Hospital, now recruiting.

## Summary

Liposomal Irinotecan (II) Fractionated Dosing Combined With 5-FU/LV (FOLFIRInali-3) and Bevacizumab in Second-line Treatment of Advanced Colorectal Cancer: A Single-arm, Phase II Clinical Study is a phase 2, interventional study registered as NCT07047560 by Tianjin Medical University Cancer Institute and Hospital, with a registry enrolment figure of 46 participants, started 2024-09-01 and due to reach its primary completion in 2026-08-01. Interventions recorded: fractionated liposomal irinotecan (II)-based combination chemotherapy (FOLFIRInali-3) plus bevacizumab (Bev). Conditions listed: Colorectal Cancer (CRC). Primary outcome: Objective Response Rate,ORR. Colorectal eligibility wording from the registry: "Patients with pathologically confirmed advanced colorectal carcinoma (all other histological types excluded);". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07047560
- Phase: 2
- Setting: Liposomal Irinotecan (II) Fractionated Dosing Combined With 5-FU/LV (FOLFIRInali-3) and Bevacizumab in Second-line Treatment of Advanced Colorectal Cancer: A Single-arm, Phase II Clinical Study
- Sponsor: Tianjin Medical University Cancer Institute and Hospital
- Enrolled: 46

## Sources

- ClinicalTrials.gov NCT07047560: https://clinicaltrials.gov/study/NCT07047560

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07047560.json