# Short Course Radiotherapy Followed by CAPOX and Carrilizumab and Bevacizumab or Cetuximab for the Initial Treatment of Unresectable Metastatic Rectal Cancer

Source: https://onco.cc/trials/nct07059949/  
OnCo record `nct07059949` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, not yet recruiting.

## Summary

Short Course Radiotherapy Followed by CAPOX and Carrilizumab and Bevacizumab or Cetuximab for the Initial Treatment of Unresectable Metastatic Rectal Cancer is a phase 2, interventional study registered as NCT07059949 by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, with a registry enrolment figure of 80 participants, started 2025-06-30 and due to reach its primary completion in 2027-01-30. Interventions recorded: CAPOX+ Camrelizumab+ Cetuximab; CAPOX+ Camrelizumab+ Bevacizumab. Conditions listed: Unresectable Metastatic Rectal Cancer; CAPOX; Combination of Radioimmunotherapy. Primary outcome: ORR. Colorectal eligibility wording from the registry: "Histologically confirmed rectal cancer with initial treatment (no surgery, radiotherapy, chemotherapy, targeted therapy or immunotherapy);". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: Union-mRC
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07059949
- Phase: 2
- Setting: Phase II, Single-center Study of Short-course Radiotherapy Followed by CAPOX and Carrelizumab and Bevacizumab or Cetuximab in the Treatment of Initially Unresectable Metastatic Rectal Cancer
- Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Enrolled: 80

## Sources

- ClinicalTrials.gov NCT07059949: https://clinicaltrials.gov/study/NCT07059949

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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