# Efficacy and Safety of FOLFOX+Cetuximab vs. FOLFOXIRI+Bevacizumab Both With QL1706 in First-Line Treatment of Left-Sided mCRC

Source: https://onco.cc/trials/nct07070713/  
OnCo record `nct07070713` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Fujian Cancer Hospital, not yet recruiting.

## Summary

Efficacy and Safety of FOLFOX+Cetuximab vs. FOLFOXIRI+Bevacizumab Both With QL1706 in First-Line Treatment of Left-Sided mCRC is a phase 2, randomised interventional study registered as NCT07070713 by Fujian Cancer Hospital, with a registry enrolment figure of 44 participants, started 2025-07-30 and due to reach its primary completion in 2028-02-28. Interventions recorded: FOLFOXIRI + QL1706 + Bevacizumab; FOLFOX+QL1706+Cetuximab. Conditions listed: Metastatic Colorectal Cancer With Left-sided Primary Tumor; Immunotherapy. Primary outcome: Objective Response Rate. Colorectal eligibility wording from the registry: "Histologically or cytologically confirmed metastatic colorectal adenocarcinoma with the primary tumor located in the left-sided colon (from the splenic flexure to the rectum), including cecal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07070713
- Phase: 2
- Setting: Assess and Compare the Efficacy and Safety of FOLFOX Combined With Cetuximab Versus FOLFOXIRI Combined With Bevacizumab When Both Used in Combination With QL1706 for First-line Treatment of Metastatic Colorectal Cancer With Left-sided Primary Tumors.
- Sponsor: Fujian Cancer Hospital
- Enrolled: 44

## Sources

- ClinicalTrials.gov NCT07070713: https://clinicaltrials.gov/study/NCT07070713

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07070713.json