# Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/ III Colorectal Cancer

Source: https://onco.cc/trials/nct07095309/  
OnCo record `nct07095309` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Metanoic Health Ltd., not yet recruiting.

## Summary

Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/ III Colorectal Cancer is a phase 2, randomised interventional study registered as NCT07095309 by Metanoic Health Ltd., with a registry enrolment figure of 120 participants, started 2025-08-15 and due to reach its primary completion in 2032-08-30. Interventions recorded: Artesunate; Artesunate matching Placebo. Conditions listed: Stage II/III Colon Cancer; Bowel Cancer. Primary outcome: Recurrence-Free Survival (RFS) at 2 Years Post-Randomisation Assessed by Radiological and Clinical Evaluation. Colorectal eligibility wording from the registry: "* Histologically proven single primary site colorectal adenocarcinoma or high grade dysplasia plus unequivocal radiological evidence of invasive cancer". Sites: Malaysia. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: NeoART-M
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07095309
- Phase: 2
- Setting: Phase II Randomised, Double Blind, Placebo Controlled Trial of Neoadjuvant Artesunate in Stage II/III Colorectal Cancer
- Sponsor: Metanoic Health Ltd.
- Enrolled: 120

## Sources

- ClinicalTrials.gov NCT07095309: https://clinicaltrials.gov/study/NCT07095309

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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