# Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer Patients

Source: https://onco.cc/trials/nct07095439/  
OnCo record `nct07095439` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Ain Shams University, now recruiting.

## Summary

Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer Patients is a phase 2, interventional study registered as NCT07095439 by Ain Shams University, with a registry enrolment figure of 38 participants, started 2023-09-01 and due to reach its primary completion in 2026-01-01. Interventions recorded: Total Neoadjuvant Treatment. Conditions listed: Rectal Cancer. Primary outcome: Pathological complete response. Colorectal eligibility wording from the registry: "* Pathologically confirmed rectal adenocarcinoma of low or mid rectum (less than 16 cm from the anal verge on endoscopy)". Sites: Egypt. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07095439
- Phase: 2
- Setting: Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer Patients
- Sponsor: Ain Shams University
- Enrolled: 38

## Sources

- ClinicalTrials.gov NCT07095439: https://clinicaltrials.gov/study/NCT07095439

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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