# A Study of GnP RegimenCombined With Serplulimab and Stereotactic Body Radiation Therapy as First-line Treatment for Locally Advanced Pancreatic Cancer

Source: https://onco.cc/trials/nct07101679/  
OnCo record `nct07101679` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in pancreatic cancer, run by West China Hospital, now recruiting.

## Summary

A Study of GnP RegimenCombined With Serplulimab and Stereotactic Body Radiation Therapy as First-line Treatment for Locally Advanced Pancreatic Cancer is a phase 2, interventional study registered as NCT07101679 by West China Hospital, with a registry enrolment figure of 23 participants, started 2025-04-16 and due to reach its primary completion in 2027-04-15. Interventions recorded: LICSBR. Conditions listed: Locally Advanced Pancreatic Ductal Adenocarcinoma. Primary outcome: Investigator-assessed Objective Response Rate (ORR). Pancreatic eligibility wording from the registry: "Inclusion Criteria (1)Histologically confirmed pancreatic ductal adenocarcinoma with diagnosis based on comprehensive assessment of pathology and imaging studies (CT or MRI), supplemented by fibroblast activation protein positron emission tomography-computed tomography (FAPI PET-CT) when necessary, ". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07101679
- Phase: 2
- Setting: A Phase II Clinical Study of GnP Regimen (Nab-paclitaxel + Gemcitabine) Combined With Serplulimab and Stereotactic Body Radiation Therapy (SBRT) as First-line Treatment for Locally Advanced Pancreatic Cancer
- Sponsor: West China Hospital
- Enrolled: 23

## Sources

- ClinicalTrials.gov NCT07101679: https://clinicaltrials.gov/study/NCT07101679

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/)
- technologies: [SBRT / SABR (stereotactic radiotherapy)](https://onco.cc/technologies/sbrt/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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