# Radiotherapy Combined QL1706, TAS-102 and Bevacizumab in mCRC

Source: https://onco.cc/trials/nct07116577/  
OnCo record `nct07116577` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of iparomlimab and tuvonralimab, trifluridine/tipiracil and bevacizumab (glioblastoma use) in colorectal cancer, run by Jinan Central Hospital, not yet recruiting.

## Summary

Radiotherapy Combined QL1706, TAS-102 and Bevacizumab in mCRC is a phase 2, interventional study registered as NCT07116577 by Jinan Central Hospital, with a registry enrolment figure of 37 participants, started 2025-08-31 and due to reach its primary completion in 2027-08-31. Interventions recorded: Palliative radiotherapy; Iparomlimab and tuvonralimab; TAS-102; Bevacizumab. Conditions listed: mCRC. Primary outcome: ORR. Colorectal eligibility wording from the registry: "* Histologically confirmed unresectable colorectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07116577
- Phase: 2
- Setting: A Single-Arm, Exploratory Study of Palliative Radiotherapy Combined With Iparomlimab and Tuvonralimab, Trifluridine/Tipiracil (TAS-102), and Bevacizumab in Later-Line Treatment of Advanced Colorectal Cancer
- Sponsor: Jinan Central Hospital
- Enrolled: 37

## Sources

- ClinicalTrials.gov NCT07116577: https://clinicaltrials.gov/study/NCT07116577

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- drugs: [Bevacizumab (glioblastoma use)](https://onco.cc/drugs/bevacizumab-glioma/), [Iparomlimab and tuvonralimab](https://onco.cc/drugs/iparomlimab-tuvonralimab/), [Trifluridine/tipiracil](https://onco.cc/drugs/trifluridine-tipiracil/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07116577.json