# Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old

Source: https://onco.cc/trials/nct07118800/  
OnCo record `nct07118800` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in colorectal cancer, run by UNICANCER, not yet recruiting.

## Summary

Study Evaluating Two Treatment Strategies for Rectal Cancer in Patients ≥75 Years Old is a phase 3, randomised interventional study registered as NCT07118800 by UNICANCER, with a registry enrolment figure of 160 participants, started 2026-07-24 and due to reach its primary completion in 2030-12-15. Interventions recorded: FOLFOX4s; Short Course Radiotherapy. Conditions listed: Locally Advanced Rectal Adenocarcinoma. Primary outcome: TME-free survival. Colorectal eligibility wording from the registry: "Histologically confirmed diagnosis of adenocarcinoma of the rectum". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: NACRE-2
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07118800
- Phase: 3
- Setting: Randomized Phase III Study Evaluating Two Treatment Strategies for Locally Advanced Rectal Cancer in Patients ≥75 Years Old
- Sponsor: UNICANCER
- Enrolled: 160

## Sources

- ClinicalTrials.gov NCT07118800: https://clinicaltrials.gov/study/NCT07118800

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- companies: [UNICANCER](https://onco.cc/companies/unicancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07118800.json