# A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer

Source: https://onco.cc/trials/nct07123441/  
OnCo record `nct07123441` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of leucovorin (folinic acid) in colorectal cancer, run by Sanjun Cai, not yet recruiting.

## Summary

A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer is a phase 2, interventional study registered as NCT07123441 by Sanjun Cai, with a registry enrolment figure of 300 participants, started 2025-09-01 and due to reach its primary completion in 2027-09-01. Interventions recorded: Bevacizumab,Irinotecan liposome (II),5-FU/LV. Conditions listed: Colorectal Cancer. Primary outcome: Safety:The incidence of adverse events. Colorectal eligibility wording from the registry: "Patients with pathologically confirmed, unresectable advanced colorectal cancer;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07123441
- Phase: 2
- Setting: A Study on the Efficacy and Safety of Irinotecan Liposome (II), 5-FU/LV in Combination With Bevacizumab for the Treatment of Advanced Colorectal Cancer
- Sponsor: Sanjun Cai
- Enrolled: 300

## Sources

- ClinicalTrials.gov NCT07123441: https://clinicaltrials.gov/study/NCT07123441

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Leucovorin (folinic acid)](https://onco.cc/drugs/leucovorin/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07123441.json