# Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction

Source: https://onco.cc/trials/nct07132190/  
OnCo record `nct07132190` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in lung cancer, run by Ayal A. Aizer, MD, now recruiting.

## Summary

Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction is a phase 2, randomised interventional study registered as NCT07132190 by Ayal A. Aizer, MD, with a registry enrolment figure of 60 participants, started 2025-12-30 and due to reach its primary completion in 2028-09. Interventions recorded: Linear accelerator-based stereotactic radiation for brain metastases using 0mm or 1mm PTV. Conditions listed: Brain Metastases, Adult; Brain Tumor - Metastatic; Brain Metastases From Non-small Cell Lung Cancer (NSCLC); Brain Metastases From Extra-cranial Solid Tumors. Primary outcome: To assess the percentage of patients that demonstrate tumor beyond the standard planning margin (1.0mm PTV) at the time of stereotactic treatment.. Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07132190
- Phase: 2
- Setting: A Double-Blind Phase II Randomized Study of Adaptively Delivered LINAC-Based Stereotactic Radiation for Volatile Brain Metastases With Same-Day Planning and Margin Reduction
- Sponsor: Ayal A. Aizer, MD
- Enrolled: 60

## Sources

- ClinicalTrials.gov NCT07132190: https://clinicaltrials.gov/study/NCT07132190

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- technologies: [SBRT / SABR (stereotactic radiotherapy)](https://onco.cc/technologies/sbrt/)
- companies: [Siemens Healthineers](https://onco.cc/companies/siemens-healthineers/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07132190.json