# PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer

Source: https://onco.cc/trials/nct07133750/  
OnCo record `nct07133750` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of PM8002 in colorectal cancer, run by Biotheus Inc., now recruiting.

## Summary

PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer is a phase 2 interventional study registered as NCT07133750 by Biotheus Inc., with 100 participants planned, started 2025-08-19 and due to reach its primary completion in 2027-05. Interventions recorded: PM8002, Chemotherapy Regimen 1, Chemotherapy Regimen 2, Chemotherapy Regimen 3. Conditions listed: CRC (Colorectal Cancer). No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT07133750
- Phase: 2
- Setting: A Phase II, Multicenter, Open Label, Parallel Cohort Clinical Trial to Evaluate the Efficacy and Safety of PM8002 (BNT327) in Combination With Chemotherapy in First Line MSS or MSI-L/pMMR Metastatic Colorectal Cancer
- Sponsor: Biotheus Inc.
- Enrolled: 100

## Sources

- ClinicalTrials.gov NCT07133750: https://clinicaltrials.gov/study/NCT07133750

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)
- drugs: [PM8002](https://onco.cc/drugs/pm8002/)
- companies: [BioNTech](https://onco.cc/companies/biontech/)

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JSON: https://onco.cc/api/v1/entities/nct07133750.json