# Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

Source: https://onco.cc/trials/nct07146646/  
OnCo record `nct07146646` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of oxaliplatin and trifluridine tipiracil in gallbladder cancer and other biliary tract cancers, run by Case Comprehensive Cancer Center, now recruiting.

## Summary

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer is a phase 2 interventional study registered as NCT07146646 by Case Comprehensive Cancer Center, with a registry enrolment figure of 27 participants, started 2025-12-01 and due to reach its primary completion in 2027-02. Interventions recorded: Trifluridine/tipiracil, Oxaliplatin. Conditions listed: Biliary Tract Cancer, Biliary Tract Neoplasms, Cholangiocarcinoma, Gallbladder Cancer, Gallbladder Carcinoma. Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; gallbladder-deep-dive
- Registry id: NCT07146646
- Phase: 2
- Setting: A Phase II Trial of Trifluridine/Tipiracil Plus Oxaliplatin in Patients With Advanced or Metastatic Biliary Tract Cancer Following First-Line Therapy
- Sponsor: Case Comprehensive Cancer Center
- Enrolled: 27

## Sources

- ClinicalTrials.gov NCT07146646: https://clinicaltrials.gov/study/NCT07146646

## Connected records

- cancers: [Ampullary cancer (ampulla of Vater)](https://onco.cc/cancers/ampullary/), [Biliary tract cancer (all types)](https://onco.cc/cancers/biliary-tract-cancer/), [Biliary tract cancer (cholangiocarcinoma)](https://onco.cc/cancers/cholangiocarcinoma/), [Gallbladder cancer](https://onco.cc/cancers/gallbladder/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [Oxaliplatin](https://onco.cc/drugs/oxaliplatin/), [Trifluridine/tipiracil](https://onco.cc/drugs/trifluridine-tipiracil/)
- terms: [Gallbladder cancer in biliary tract cancer trials (eligibility and subgroups)](https://onco.cc/terms/gallbladder-cancer-in-biliary-trials/)

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