# Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)

Source: https://onco.cc/trials/nct07155200/  
OnCo record `nct07155200` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of fOLFIRI (5-FU, leucovorin, irinotecan) in lung cancer, run by Washington University School of Medicine, now recruiting.

## Summary

Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial) is a phase 1/2, interventional study registered as NCT07155200 by Washington University School of Medicine, with a registry enrolment figure of 42 participants, started 2025-12-18 and due to reach its primary completion in 2028-07-31. Interventions recorded: Cirtuvivint; Irinotecan. Conditions listed: Small-cell Lung Cancer; Small Cell Lung Carcinoma; Small Cell Lung Cancer. Primary outcome: Recommended Phase II dose (RP2D) (Phase I only); Objective response rate (ORR) per RECIST criteria (Phase II and RP2D only). Lung eligibility wording from the registry: "* Histologically or cytologically confirmed small cell lung cancer that has progressed on at least one line of prior platinum-based chemotherapy, given with or without anti-PD-(L)1 therapy". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT07155200
- Phase: 1/2
- Setting: Small Cell Lung Cancer Irinotecan and CDC2-like Kinase Inhibition Trial (SLICK Trial)
- Sponsor: Washington University School of Medicine
- Enrolled: 42

## Sources

- ClinicalTrials.gov NCT07155200: https://clinicaltrials.gov/study/NCT07155200

## Connected records

- cancers: [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- drugs: [FOLFIRI (5-FU, leucovorin, irinotecan)](https://onco.cc/drugs/folfiri/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07155200.json