# QL1706 Plus XELOX as Neoadjuvant Therapy for MSS/pMMR Clinical Stage III Colon Cancer

Source: https://onco.cc/trials/nct07156682/  
OnCo record `nct07156682` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of QL1706 and cAPOX (capecitabine, oxaliplatin) in colorectal cancer, run by Qilu Hospital of Shandong University, not yet recruiting.

## Summary

QL1706 Plus XELOX as Neoadjuvant Therapy for MSS/pMMR Clinical Stage III Colon Cancer is a phase 2, interventional study registered as NCT07156682 by Qilu Hospital of Shandong University, with a registry enrolment figure of 21 participants, started 2025-09-25 and due to reach its primary completion in 2027-06-30. Interventions recorded: QL1706; XELOX. Conditions listed: Colon Cancer; MSS/pMMR; QL1706. Primary outcome: Pathological Complete Response (pCR). Colorectal eligibility wording from the registry: "* Histologically or clinically confirmed initially resectable Stage III colon cancer according to the AJCC 8th edition". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07156682
- Phase: 2
- Setting: A Single-Arm, Exploratory Study of Iparomlimab and Tuvonralimab (QL1706) Plus XELOX as Neoadjuvant Therapy in Patients With Microsatellite Stable (pMMR/MSS) Resectable Stage III Colon Cancer
- Sponsor: Qilu Hospital of Shandong University
- Enrolled: 21

## Sources

- ClinicalTrials.gov NCT07156682: https://clinicaltrials.gov/study/NCT07156682

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [CAPOX (capecitabine, oxaliplatin)](https://onco.cc/drugs/capox/), [QL1706](https://onco.cc/drugs/ql1706/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07156682.json