# QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer

Source: https://onco.cc/trials/nct07175636/  
OnCo record `nct07175636` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Sun Yat-sen University, not yet recruiting.

## Summary

QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal Cancer is a phase 2, interventional study registered as NCT07175636 by Sun Yat-sen University, with a registry enrolment figure of 66 participants, started 2025-09-20 and due to reach its primary completion in 2026-09-20. Interventions recorded: Drug: QL1706 Drug: mFOLFOX6 Radiation: Short-Course Radiotherapy (SCRT). Conditions listed: Locally Advanced Rectal Cancer (LARC); Mismatch Repair-Proficient (pMMR) Rectal Cancer; Non-metastatic Rectal Cancer. Primary outcome: Pathologic Complete Response (pCR) Rate. Colorectal eligibility wording from the registry: "Histologically confirmed rectal adenocarcinoma". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07175636
- Phase: 2
- Setting: A Multicenter, Prospective, Phase II Clinical Trial of Short-Course Radiotherapy Followed by QL1706 Plus mFOLFOX6 as Total Neoadjuvant Therapy for Patients With pMMR/MSS Locally Advanced Rectal Cancer
- Sponsor: Sun Yat-sen University
- Enrolled: 66

## Sources

- ClinicalTrials.gov NCT07175636: https://clinicaltrials.gov/study/NCT07175636

## Connected records

- cancers: [Mismatch-repair deficient (MSI-high) colorectal cancer](https://onco.cc/cancers/msi-high-colorectal/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct07175636.json