# Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer

Source: https://onco.cc/trials/nct07199764/  
OnCo record `nct07199764` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of mitazalimab in pancreatic cancer, run by University of Pennsylvania, now recruiting.

## Summary

Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer is a phase 2, interventional study registered as NCT07199764 by University of Pennsylvania, with a registry enrolment figure of 100 participants, started 2025-11-25 and due to reach its primary completion in 2027-10. Interventions recorded: Odetiglucan; Mitazalimab. Conditions listed: Pancreatic Ductal Adenocarcinoma. Primary outcome: Median progression-free survival (mPFS) of 7.5 months in Cohort A. Pancreatic eligibility wording from the registry: "* Histologically or cytologically confirmed diagnosis of pancreatic adenocarcinoma that is either locally advanced and unresectable, or metastatic". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: IGNITE
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT07199764
- Phase: 2
- Setting: IGNITE: A Phase 2 Study of Maintenance Combinatorial Myeloid Immunotherapy in Patients With Unresectable Pancreatic Ductal Adenocarcinoma
- Sponsor: University of Pennsylvania
- Enrolled: 100

## Sources

- ClinicalTrials.gov NCT07199764: https://clinicaltrials.gov/study/NCT07199764

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- drugs: [Mitazalimab](https://onco.cc/drugs/mitazalimab/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct07199764.json