# Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer

Source: https://onco.cc/trials/nct07200141/  
OnCo record `nct07200141` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Peking Union Medical College Hospital, now recruiting.

## Summary

Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer is a phase 2, randomised interventional study registered as NCT07200141 by Peking Union Medical College Hospital, with a registry enrolment figure of 156 participants, started 2025-10-01 and due to reach its primary completion in 2026-12-01. Interventions recorded: GTV 58.75 Gy/25 fractions(Simultaneous Integrated Boost); GTV 50 Gy/25 fractions(Simultaneous Integrated Boost); Concurrent Chemotherapy; Total mesorectal excision (TME) surgery or non-operative management. Conditions listed: Locally Advanced Rectal Adenocarcinoma. Primary outcome: CR. Colorectal eligibility wording from the registry: "Histologically confirmed rectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: SIB-NCRT
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT07200141
- Phase: 2
- Setting: Simultaneous Boost in Neoadjuvant Radiotherapy for Rectal Cancer：A Phase 2, Randomized Controlled Study
- Sponsor: Peking Union Medical College Hospital
- Enrolled: 156

## Sources

- ClinicalTrials.gov NCT07200141: https://clinicaltrials.gov/study/NCT07200141

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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