# A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)

Source: https://onco.cc/trials/nct07213882/  
OnCo record `nct07213882` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1 trial of DT-7012 run by Assistance Publique - Hôpitaux de Paris, not yet recruiting.

## Summary

A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL) is a phase 1 interventional study registered as NCT07213882 by Assistance Publique - Hôpitaux de Paris, with 30 participants planned, started 2026-01-01. Conditions recorded: Cutaneous T Cell Lymphoma (CTCL), Mycosis Fungoides and Sezary Syndrome. Interventions recorded: DT-7012.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-11-03
- Tags: pipeline; ctgov-ingest
- Registry id: NCT07213882
- Phase: 1
- Setting: A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)
- Sponsor: Assistance Publique - Hôpitaux de Paris
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT07213882: https://clinicaltrials.gov/study/NCT07213882

## Connected records

- cancers: [Cutaneous T-cell lymphoma (mycosis fungoides and Sezary syndrome)](https://onco.cc/cancers/cutaneous-t-cell-lymphoma/), [Mycosis fungoides](https://onco.cc/cancers/mycosis-fungoides/), [Non-Hodgkin lymphoma (all types)](https://onco.cc/cancers/non-hodgkin-lymphoma/)
- drugs: [DT-7012](https://onco.cc/drugs/dt-7012/)
- companies: [Kainova Therapeutics](https://onco.cc/companies/domain-therapeutics/)

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